12+
Available Cruises
50+
Destinations
3-21
nights
5+
Cruise Lines
Discover cruises from Colon
Colon is an excellent starting point for some of the world's most exciting cruise destinations.
Featured cruises from Colon
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Royal Caribbean International
Grandeur of the Seas
$307
per personRoyal Caribbean International
Grandeur of the Seas
$283
per personRoyal Caribbean International
Grandeur of the Seas
$272
per personRoyal Caribbean International
Grandeur of the Seas
$254
per personRoyal Caribbean International
Grandeur of the Seas
$232
per personRoyal Caribbean International
Grandeur of the Seas
$243
per personGet the best prices on cruises from Colon:
- Book 6-12 months ahead for best cabin selection
- Consider shoulder season for savings
- Subscribe to cruise line newsletters for deals
- Compare prices across different cruise lines
Optimal times to cruise from Colon:
- Spring (March-May): Pleasant weather, fewer tourists
- Summer (June-August): Perfect for families
- Fall (September-November): Great prices, beautiful weather
- Winter (December-February): Warm destination cruises
More cruises from Colon
Royal Caribbean International
Grandeur of the Seas
$249
per personRoyal Caribbean International
Grandeur of the Seas
$203
per personRoyal Caribbean International
Grandeur of the Seas
$266
per personRoyal Caribbean International
Grandeur of the Seas
$295
per personRoyal Caribbean International
Grandeur of the Seas
$255
per personRoyal Caribbean International
Grandeur of the Seas
$232
per personReady to sail from Colon?
Find your perfect cruise today and start your adventure