Cruises with MSC Cruises in Panama Canal

490 cruises
€330 from for 3 nights
7 nights from €1,046
16.11.2026 - 10.11.2028
5 ports
Cruises with MSC Cruises in Panama Canal: itineraries, embarkation ports and departure dates.
MSC Opera
MSC Cruises
MSC Opera
Panama Canal
27.12.2027 · 14 nights Port of departure: La Romana, Dominican Republic Base fare, no drinks

La Romana, Dominican Republic, Catalina Island, Dominican Rep, Virgin Gorda, B.V.i., Philipsburg, St. Maarten, Basseterre, Saint Kitts, Nevis, St John S, Antigua and Barbuda, La Romana, Dominican Republic, Catalina Island, Dominican Rep, Oranjestad, Aruba, Willemstad, Curacao, Kralendijk, Bonaire, Saint George, Grenada, La Romana, Dominican Republic

from €4,374
I Interior €4,374
O Ocean View €5,054
B Balcony €6,454

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MSC Opera
MSC Cruises
MSC Opera
Panama Canal
23.11.2026 · 14 nights Port of departure: La Romana, Dominican Republic Base fare, no drinks

La Romana, Dominican Republic, Samana, Dominican Republic, Virgin Gorda, B.V.i., Philipsburg, St. Maarten, Basseterre, Saint Kitts, Nevis, Catalina Island, Dominican Rep, La Romana, Dominican Republic, Catalina Island, Dominican Rep, Bridgetown, Barbados, Fort de France, Martinique, Pointe-A-Pitre, Guadalupe, Tortola/Road Town, VG, La Romana, Dominican Republic

from €4,374
I Interior €4,374
O Ocean View €4,374
B Balcony €5,574

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MSC Opera
MSC Cruises
MSC Opera
Panama Canal
14.12.2026 · 14 nights Port of departure: La Romana, Dominican Republic Base fare, no drinks

La Romana, Dominican Republic, Catalina Island, Dominican Rep, Bridgetown, Barbados, Fort de France, Martinique, Pointe-A-Pitre, Guadalupe, Tortola/Road Town, VG, La Romana, Dominican Republic, Samana, Dominican Republic, Virgin Gorda, B.V.i., Basseterre, Saint Kitts, Nevis, Philipsburg, St. Maarten, Catalina Island, Dominican Rep, La Romana, Dominican Republic

from €4,494
I Interior €4,494
O Ocean View €4,494
B Balcony €6,194

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MSC Opera
MSC Cruises
MSC Opera
Panama Canal
07.12.2026 · 14 nights Port of departure: La Romana, Dominican Republic Base fare, no drinks

La Romana, Dominican Republic, Virgin Gorda, B.V.i., Philipsburg, St. Maarten, Basseterre, Saint Kitts, Nevis, Tortola/Road Town, VG, Catalina Island, Dominican Rep, La Romana, Dominican Republic, Catalina Island, Dominican Rep, Bridgetown, Barbados, Fort de France, Martinique, Pointe-A-Pitre, Guadalupe, Tortola/Road Town, VG, La Romana, Dominican Republic

from €4,494
I Interior €4,494
O Ocean View €4,494
B Balcony €6,114

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MSC Opera
MSC Cruises
MSC Opera
Panama Canal
04.01.2027 · 14 nights Port of departure: La Romana, Dominican Republic Base fare, no drinks

La Romana, Dominican Republic, Samana, Dominican Republic, Virgin Gorda, B.V.i., Basseterre, Saint Kitts, Nevis, Philipsburg, St. Maarten, Catalina Island, Dominican Rep, La Romana, Dominican Republic, Catalina Island, Dominican Rep, Bridgetown, Barbados, Fort de France, Martinique, St John S, Antigua and Barbuda, Virgin Gorda, B.V.i., La Romana, Dominican Republic

from €4,614
I Interior €4,614
O Ocean View €4,614
B Balcony €6,094

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MSC Opera
MSC Cruises
MSC Opera
Panama Canal
18.12.2026 · 14 nights Port of departure: Fort de France, Martinique Base fare, no drinks

Fort de France, Martinique, Pointe-A-Pitre, Guadalupe, Tortola/Road Town, VG, La Romana, Dominican Republic, Samana, Dominican Republic, Virgin Gorda, B.V.i., Basseterre, Saint Kitts, Nevis, Philipsburg, St. Maarten, Catalina Island, Dominican Rep, La Romana, Dominican Republic, Catalina Island, Dominican Rep, Bridgetown, Barbados, Fort de France, Martinique

from €4,854
I Interior €4,854
O Ocean View €4,854
B Balcony €5,834

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MSC Opera
MSC Cruises
MSC Opera
Panama Canal
20.12.2027 · 14 nights Port of departure: La Romana, Dominican Republic Base fare, no drinks

La Romana, Dominican Republic, Catalina Island, Dominican Rep, Oranjestad, Aruba, Willemstad, Curacao, Kralendijk, Bonaire, Saint George, Grenada, La Romana, Dominican Republic, Catalina Island, Dominican Rep, Virgin Gorda, B.V.i., Philipsburg, St. Maarten, Basseterre, Saint Kitts, Nevis, St John S, Antigua and Barbuda, La Romana, Dominican Republic

from €4,974
I Interior €4,974
O Ocean View €5,654
B Balcony €7,054

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MSC Opera
MSC Cruises
MSC Opera
Panama Canal
15.03.2027 · 14 nights Port of departure: La Romana, Dominican Republic Base fare, no drinks

La Romana, Dominican Republic, Virgin Gorda, B.V.i., Philipsburg, St. Maarten, Basseterre, Saint Kitts, Nevis, Tortola/Road Town, VG, Catalina Island, Dominican Rep, La Romana, Dominican Republic, Catalina Island, Dominican Rep, Oranjestad, Aruba, Willemstad, Curacao, Kralendijk, Bonaire, Saint George, Grenada, La Romana, Dominican Republic

from €5,174
I Interior €5,174
O Ocean View €5,174
B Balcony €6,674

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MSC Opera
MSC Cruises
MSC Opera
Panama Canal
22.03.2027 · 14 nights Port of departure: La Romana, Dominican Republic Base fare, no drinks

La Romana, Dominican Republic, Catalina Island, Dominican Rep, Oranjestad, Aruba, Willemstad, Curacao, Kralendijk, Bonaire, Saint George, Grenada, La Romana, Dominican Republic, Catalina Island, Dominican Rep, Virgin Gorda, B.V.i., Philipsburg, St. Maarten, Basseterre, Saint Kitts, Nevis, St John S, Antigua and Barbuda, La Romana, Dominican Republic

from €5,334
I Interior €5,334
O Ocean View €5,334
B Balcony €6,634

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MSC Opera
MSC Cruises
MSC Opera
Panama Canal
28.12.2026 · 14 nights Port of departure: La Romana, Dominican Republic Base fare, no drinks

La Romana, Dominican Republic, Catalina Island, Dominican Rep, Bridgetown, Barbados, Fort de France, Martinique, St John S, Antigua and Barbuda, Tortola/Road Town, VG, La Romana, Dominican Republic, Samana, Dominican Republic, Virgin Gorda, B.V.i., Basseterre, Saint Kitts, Nevis, Philipsburg, St. Maarten, Catalina Island, Dominican Rep, La Romana, Dominican Republic

from €8,114
I Interior €8,114
O Ocean View €8,114
B Balcony €9,314

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Panama Canal View cruise line

By month

November 2026 · 9 December 2026 · 34 January 2027 · 38 February 2027 · 34 March 2027 · 33 April 2027 · 19 May 2027 · 16 June 2027 · 14 July 2027 · 15 August 2027 · 16 September 2027 · 15 October 2027 · 15

Popular embarkation ports

La Romana, Dominican Republic 205 Fort de France, Martinique 158 Bridgetown, Barbados 77 Pointe-A-Pitre, Guadalupe 49 Miami, Florida 1

Other cruise lines in this region

Norwegian Cruise Line 34 Celebrity Cruises 8
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