Cruises with MSC Cruises in South America and Antarctica

401 cruises
€122 from for 1 night
6 nights from €910
12.11.2026 - 16.04.2028
8 ports
Cruises with MSC Cruises in South America and Antarctica: itineraries, embarkation ports and departure dates.
MSC Splendida
MSC Cruises
MSC Splendida
South America and Antarctica
15.02.2028 · 9 nights Port of departure: Rio de Janeiro, Brazil Base fare, no drinks

Rio de Janeiro, Brazil, Buzios, Brazil, Ilhabela, Brazil, Camboriu, Brazil, Punta del Este, Uruguay, Buenos Aires, Argentina, Rio de Janeiro, Brazil

from €2,306
I Interior €2,306
O Ocean View €2,566
B Balcony €3,166
S Suite €4,126

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MSC Splendida
MSC Cruises
MSC Splendida
South America and Antarctica
03.02.2028 · 9 nights Port of departure: Buenos Aires, Argentina Base fare, no drinks

Buenos Aires, Argentina, Rio de Janeiro, Brazil, Buzios, Brazil, Ilhabela, Brazil, Camboriu, Brazil, Punta del Este, Uruguay, Buenos Aires, Argentina

from €2,306
I Interior €2,306
O Ocean View €2,566
B Balcony €3,166
S Suite €4,126

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MSC Splendida
MSC Cruises
MSC Splendida
South America and Antarctica
06.02.2028 · 9 nights Port of departure: Rio de Janeiro, Brazil Base fare, no drinks

Rio de Janeiro, Brazil, Buzios, Brazil, Ilhabela, Brazil, Camboriu, Brazil, Punta del Este, Uruguay, Buenos Aires, Argentina, Rio de Janeiro, Brazil

from €2,306
I Interior €2,306
O Ocean View €2,566
B Balcony €3,166
S Suite €4,126

Press "Details" button to see an actual price. Price per cabin.

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MSC Splendida
MSC Cruises
MSC Splendida
South America and Antarctica
12.02.2028 · 9 nights Port of departure: Buenos Aires, Argentina Base fare, no drinks

Buenos Aires, Argentina, Rio de Janeiro, Brazil, Buzios, Brazil, Ilhabela, Brazil, Camboriu, Brazil, Punta del Este, Uruguay, Buenos Aires, Argentina

from €2,306
I Interior €2,306
O Ocean View €2,566
B Balcony €3,166
S Suite €4,126

Press "Details" button to see an actual price. Price per cabin.

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MSC Virtuosa
MSC Cruises
MSC Virtuosa
South America and Antarctica
29.12.2027 · 7 nights Port of departure: Salvador de Bahia, Brazil Base fare, no drinks

Salvador de Bahia, Brazil, Copacabana Beach, Brazil, Copacabana Beach, Brazil, Ilhabela, Brazil, Santos, Brazil, Buzios, Brazil, Salvador de Bahia, Brazil

from €2,353
I Interior €2,353
O Ocean View €3,342
B Balcony €3,093

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MSC Meraviglia
MSC Cruises
MSC Meraviglia
South America and Antarctica
19.12.2027 · 8 nights Port of departure: Santos, Brazil Base fare, no drinks

Santos, Brazil, Camboriu, Brazil, Punta del Este, Uruguay, Buenos Aires, Argentina, Montevideo, Santos, Brazil

from €2,374
I Interior €2,374
O Ocean View €2,814
B Balcony €2,755

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MSC Meraviglia
MSC Cruises
MSC Meraviglia
South America and Antarctica
20.12.2027 · 8 nights Port of departure: Camboriu, Brazil Base fare, no drinks

Camboriu, Brazil, Punta del Este, Uruguay, Buenos Aires, Argentina, Montevideo, Santos, Brazil, Camboriu, Brazil

from €2,374
I Interior €2,374
O Ocean View €2,814
B Balcony €2,755

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MSC Virtuosa
MSC Cruises
MSC Virtuosa
South America and Antarctica
18.12.2027 · 8 nights Port of departure: Santos, Brazil Base fare, no drinks

Santos, Brazil, Buzios, Brazil, Salvador de Bahia, Brazil, Maceio, Ilha Grande, Brazil, Santos, Brazil

from €2,394
I Interior €2,394
O Ocean View €2,834
B Balcony €2,755

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MSC Splendida
MSC Cruises
MSC Splendida
South America and Antarctica
19.01.2028 · 9 nights Port of departure: Rio de Janeiro, Brazil Base fare, no drinks

Rio de Janeiro, Brazil, Buzios, Brazil, Ilhabela, Brazil, Camboriu, Brazil, Punta del Este, Uruguay, Buenos Aires, Argentina, Rio de Janeiro, Brazil

from €2,486
I Interior €2,486
O Ocean View €2,746
B Balcony €3,346
S Suite €4,306

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MSC Splendida
MSC Cruises
MSC Splendida
South America and Antarctica
10.01.2028 · 9 nights Port of departure: Rio de Janeiro, Brazil Base fare, no drinks

Rio de Janeiro, Brazil, Buzios, Brazil, Ilhabela, Brazil, Camboriu, Brazil, Punta del Este, Uruguay, Buenos Aires, Argentina, Rio de Janeiro, Brazil

from €2,486
I Interior €2,486
O Ocean View €2,746
B Balcony €3,346
S Suite €4,306

Press "Details" button to see an actual price. Price per cabin.

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South America and Antarctica View cruise line

By month

November 2026 · 12 December 2026 · 54 January 2027 · 51 February 2027 · 51 March 2027 · 43 April 2027 · 4 November 2027 · 6 December 2027 · 41 January 2028 · 50 February 2028 · 53 March 2028 · 31 April 2028 · 5

Popular embarkation ports

Santos, Brazil 148 Buenos Aires, Argentina 57 Rio de Janeiro, Brazil 57 Salvador de Bahia, Brazil 35 Camboriu, Brazil 29 Maceio 28 Itajai 24 Paranagua, Brazil 23

Other cruise lines in this region

Norwegian Cruise Line 6 Costa Cruises 22 Celebrity Cruises 466
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