Cruises with MSC Cruises in South America and Antarctica

401 cruises
€122 from for 1 night
6 nights from €910
12.11.2026 - 16.04.2028
8 ports
Cruises with MSC Cruises in South America and Antarctica: itineraries, embarkation ports and departure dates.
MSC Virtuosa
MSC Cruises
MSC Virtuosa
South America and Antarctica
05.02.2028 · 7 nights Port of departure: Santos, Brazil Base fare, no drinks

Santos, Brazil, Buzios, Brazil, Salvador de Bahia, Brazil, Maceio, Santos, Brazil

from €1,842
I Interior €1,842
O Ocean View €2,142
B Balcony €2,173

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MSC Splendida
MSC Cruises
MSC Splendida
South America and Antarctica
16.03.2028 · 8 nights Port of departure: Buenos Aires, Argentina Base fare, no drinks

Buenos Aires, Argentina, Rio de Janeiro, Brazil, Ilhabela, Brazil, Camboriu, Brazil, Punta del Este, Uruguay, Buenos Aires, Argentina

from €1,854
I Interior €1,854
O Ocean View €2,074
B Balcony €2,634
S Suite €3,494

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MSC Splendida
MSC Cruises
MSC Splendida
South America and Antarctica
19.03.2028 · 8 nights Port of departure: Rio de Janeiro, Brazil Base fare, no drinks

Rio de Janeiro, Brazil, Ilhabela, Brazil, Camboriu, Brazil, Punta del Este, Uruguay, Buenos Aires, Argentina, Rio de Janeiro, Brazil

from €1,854
I Interior €1,854
O Ocean View €2,074
B Balcony €2,634
S Suite €3,494

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MSC Musica
MSC Cruises
MSC Musica
South America and Antarctica
06.02.2027 · 7 nights Port of departure: Paranagua, Brazil Base fare, no drinks

Paranagua, Brazil, Itajai, Ilhabela, Brazil, Rio de Janeiro, Brazil, Buzios, Brazil, Ilha Grande, Brazil, Paranagua, Brazil

from €1,862
I Interior €1,862
O Ocean View €2,162
B Balcony €2,162

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MSC Musica
MSC Cruises
MSC Musica
South America and Antarctica
07.02.2027 · 7 nights Port of departure: Itajai Base fare, no drinks

Itajai, Ilhabela, Brazil, Rio de Janeiro, Brazil, Buzios, Brazil, Ilha Grande, Brazil, Paranagua, Brazil, Itajai

from €1,862
I Interior €1,862
O Ocean View €2,162
B Balcony €2,162

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MSC Virtuosa
MSC Cruises
MSC Virtuosa
South America and Antarctica
19.12.2026 · 7 nights Port of departure: Santos, Brazil Base fare, no drinks

Santos, Brazil, Buzios, Brazil, Salvador de Bahia, Brazil, Maceio, Santos, Brazil

from €1,893
I Interior €1,903
O Ocean View €2,602
B Balcony €1,893

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MSC Virtuosa
MSC Cruises
MSC Virtuosa
South America and Antarctica
22.12.2026 · 7 nights Port of departure: Salvador de Bahia, Brazil Base fare, no drinks

Salvador de Bahia, Brazil, Maceio, Santos, Brazil, Buzios, Brazil, Salvador de Bahia, Brazil

from €1,893
I Interior €1,903
O Ocean View €2,602
B Balcony €1,893

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MSC Musica
MSC Cruises
MSC Musica
South America and Antarctica
22.12.2026 · 7 nights Port of departure: Rio de Janeiro, Brazil Base fare, no drinks

Rio de Janeiro, Brazil, Ilha Grande, Brazil, Buzios, Brazil, Paranagua, Brazil, Itajai, Ilhabela, Brazil, Rio de Janeiro, Brazil

from €1,902
I Interior €1,902
O Ocean View €2,202
B Balcony €2,202

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MSC Virtuosa
MSC Cruises
MSC Virtuosa
South America and Antarctica
27.03.2027 · 7 nights Port of departure: Santos, Brazil Base fare, no drinks

Santos, Brazil, Buzios, Brazil, Salvador de Bahia, Brazil, Maceio, Santos, Brazil

from €1,913
I Interior €1,923
O Ocean View €2,482
B Balcony €1,913

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MSC Musica
MSC Cruises
MSC Musica
South America and Antarctica
09.02.2027 · 7 nights Port of departure: Rio de Janeiro, Brazil Base fare, no drinks

Rio de Janeiro, Brazil, Buzios, Brazil, Ilha Grande, Brazil, Paranagua, Brazil, Itajai, Ilhabela, Brazil, Rio de Janeiro, Brazil

from €1,922
I Interior €1,922
O Ocean View €2,162
B Balcony €2,162

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South America and Antarctica View cruise line

By month

November 2026 · 12 December 2026 · 54 January 2027 · 51 February 2027 · 51 March 2027 · 43 April 2027 · 4 November 2027 · 6 December 2027 · 41 January 2028 · 50 February 2028 · 53 March 2028 · 31 April 2028 · 5

Popular embarkation ports

Santos, Brazil 148 Buenos Aires, Argentina 57 Rio de Janeiro, Brazil 57 Salvador de Bahia, Brazil 35 Camboriu, Brazil 29 Maceio 28 Itajai 24 Paranagua, Brazil 23

Other cruise lines in this region

Norwegian Cruise Line 6 Costa Cruises 22 Celebrity Cruises 466
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